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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K9
All Species:
27.88
Human Site:
T404
Identified Species:
55.76
UniProt:
P80192
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P80192
NP_149132.2
1104
121895
T404
T
N
I
L
D
Q
L
T
T
I
E
E
S
G
F
Chimpanzee
Pan troglodytes
XP_001146659
1107
121909
T407
T
N
I
L
D
Q
L
T
T
I
E
E
S
G
F
Rhesus Macaque
Macaca mulatta
XP_001083417
1104
121935
T404
T
N
I
L
D
Q
L
T
T
I
E
E
S
G
F
Dog
Lupus familis
XP_547887
1216
135201
T516
T
N
I
L
D
Q
L
T
T
I
E
E
S
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1V8
1077
118787
T397
T
S
I
L
D
Q
L
T
T
I
E
E
S
G
F
Rat
Rattus norvegicus
Q66HA1
850
93091
E260
P
I
E
G
D
D
M
E
H
K
T
L
K
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7T2V3
1005
111856
T378
S
C
I
L
E
Q
L
T
T
I
E
Q
S
A
M
Zebra Danio
Brachydanio rerio
XP_689128
1009
111927
T396
T
S
I
L
D
Q
L
T
A
I
E
E
S
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95UN8
1161
128942
E400
K
E
I
L
K
Q
L
E
S
I
A
C
S
K
F
Honey Bee
Apis mellifera
XP_395037
1102
123539
D459
A
E
I
L
V
A
L
D
E
V
R
S
A
F
A
Nematode Worm
Caenorhab. elegans
O01700
928
103465
N323
T
R
E
T
P
Y
A
N
I
A
Q
M
A
I
I
Sea Urchin
Strong. purpuratus
XP_001195574
960
106888
T350
G
I
A
V
N
K
L
T
L
P
I
P
S
T
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99
81.4
N.A.
92.9
43
N.A.
N.A.
N.A.
53.8
58.9
N.A.
30.8
38.6
22.1
39.4
Protein Similarity:
100
98.1
99.5
84.2
N.A.
94.6
55.2
N.A.
N.A.
N.A.
66.4
69.4
N.A.
46
53.8
38.6
55.7
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
N.A.
N.A.
60
86.6
N.A.
46.6
20
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
N.A.
80
93.3
N.A.
53.3
33.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
9
9
0
9
9
9
0
17
9
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
9
% C
% Asp:
0
0
0
0
59
9
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
17
17
0
9
0
0
17
9
0
59
50
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
59
% F
% Gly:
9
0
0
9
0
0
0
0
0
0
0
0
0
50
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
17
75
0
0
0
0
0
9
67
9
0
0
17
9
% I
% Lys:
9
0
0
0
9
9
0
0
0
9
0
0
9
9
0
% K
% Leu:
0
0
0
75
0
0
84
0
9
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
9
% M
% Asn:
0
34
0
0
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
9
0
0
0
0
9
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
67
0
0
0
0
9
9
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
9
17
0
0
0
0
0
0
9
0
0
9
75
0
0
% S
% Thr:
59
0
0
9
0
0
0
67
50
0
9
0
0
9
9
% T
% Val:
0
0
0
9
9
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _